NM_001143805.1 → NP_001137277.1 brain-derived neurotrophic factor isoform a preproprotein NG_011794.2 RefSeqGene Range 26575.72137 Download GenBank, FASTA, Sequence Viewer (Graphics) This section to the one reported in Genomic regions, Identify version mismatches by comparing the version of the RefSeq in These reference sequences are curated independently of the genomeĪnnotation cycle, so their versions may not match the RefSeq versions in the current These reference sequences exist independently of genome builds. Expression Biased expression in brain (RPKM 3.0), lung (RPKM 1.2) and 11 other tissues See more Orthologs mouse all NEW Try the new Gene table This gene may play a role in the regulation of the stress response and in the biology of mood disorders. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Full Name brain derived neurotrophic factor provided by HGNC Primary source HGNC:HGNC:1033 See related Ensembl:ENSG00000176697 MIM:113505 AllianceGenome:HGNC:1033 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as ANON2 BULN2 Summary This gene encodes a member of the nerve growth factor family of proteins.
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